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Catalpol attenuates OGD/R damage to cortical neurons via miRNA124 mediated regulation of PI3K/AKT/mTOR/p-S6/GAP-43 pathway. (A,B,C) mRNA expression of PI3K, AKT and S6 in each group (qRT-PCR); (D,G) protein expression of p-mTOR, t-mTOR, p-S6 and GAP-43 in each group (Western blotting); (E,F,H) quantification of p-mTOR/t-mTOR, p-S6 and GAP-43 protein expression. Data are presented as means ± SD, n=6, *, P<0.05 vs. model. SD, standard deviation.
