Table 5. The relationship between the chromosomal abnormalities and age of the AMA women.
| Age | n (%) | Number abnormalities, n (%) | Structural abnormalities, n (%) |
|---|---|---|---|
| 35 | 968 (22.9) | 26 (2.7) | 6 (0.6) |
| 36 | 895 (21.2) | 16 (1.8) | 2 (0.2) |
| 37 | 688 (16.3) | 16 (2.3) | 6 (0.9) |
| 38 | 539 (12.8) | 32 (5.9) | 0 |
| 39 | 386 (9.1) | 7 (1.8) | 2 (0.5) |
| 40 | 295 (7.0) | 16 (5.4) | 0 |
| 41 | 206 (4.9) | 15 (7.3) | 1 (0.5) |
| 42 | 119 (2.8) | 4 (3.4) | 2 (1.7) |
| ≥43 | 128 (3.0) | 13 (10.2) | 0 |
| Total | 4,224 [100] | 145 (3.4) | 19 (0.4) |
The increasing trend of abnormalities rate with age was analyzed by Cochran-Armitage test, and alternative hypothesis was “increasing trend”. P<0.001 for number abnormalities, and P=0.624 for structural abnormalities. AMA, advanced maternal age.