Fig. 4.

(A–E) Patient 1 with LGI1 IgG limbic encephalitis. Brain MRI (FLAIR sequence) demonstrating bilateral medial temporal hyperintensities on axial (A) and sagittal (B) sections. Patient 2 with ANNA-1 IgG limbic encephalitis. Brain MRI (FLAIR sequence) demonstrating bilateral medial temporal hyperintensities on axial (C) and sagittal (D) sections. Patient 3 with Ma-2 IgG limbic encephalitis. Brain MRI (FLAIR sequence) demonstrating bilateral medial temporal (right greater than left) hyperintensities on axial (E) and sagittal (F) sections. ANNA-1 = antineuronal nuclear antibody-1; FLAIR = fluid-attenuated inversion recovery; LGI1 = leucine-rich glioma-inactivated protein 1