. 2019 Jul 24;9(3):279–291. doi: 10.1007/s13534-019-00122-y

Table 2.

State-of-the-art LSM technology and associated imaging parameters

Technique	Lateral resolution (µm)	Axial resolution (µm)	Field of view
Ultra microscopy [orthogonal-plane fluorescence Optical o sectioning (OPFOS)]	10	26	1.5 mm (FOV)
Thin light sheet microscopy (2002)	10	23	1 mm (FOV)
Selective plane illumination microscopy (SPIM) (2004)	1	3–10	1.5 × 0.9 mm²
SCAPE	0.4–2	0.5–3	0.6 × 1 × 0.55 mm³
Open-top LSM	1.4	7	3.3 × 3.3 × 1.28 mm³ (4 × objective lens) (optically cleared human biopsy specimen)
Light sheet theta microscopy (LSTM)	0.4–2	2–5	1.3 × 1.3 × 3 mm³ (10 × objective lens) (optically cleared human brain tissue)