Fig. 5.

FMD modifies the dysbiosis of gut microbiota induced by MPTP based on 16S rRNA sequencing. (a–c) Analysis of alpha diversity-based, 16S rRNA sequencing-predicted gut microbiota richness by the Chao1 index (a), diversity by the Shannon index (b) and the number of OTUs by observed_otus (c). (d) Comparison of the fecal microbiota structures and distribution at the phylum-based 16S rRNA sequencing level. (e) Heatmap based on the Bray–Curtis distance analysis of 16S rRNA showing relative abundance of gut microbiota at the phylum level. (f) Relative abundance of gut microbiota changed significantly at the genus level, based on 16S rRNA sequencing. NA = NS-AL group; NF = NS-FMD group; MA = MPTP-AL group; MF = MPTP-FMD group. n = 10 mice per group