TABLE 3.
Associations between metabolic risk factors, insulin resistance and POCD.
| Crude OR | 95% CI | P-value | Multivariable adjusted OR | 95% CI | P-value | |
| Metabolic characteristics | ||||||
| Fasting plasma glucose | 1.638 | 1.235–2.174 | 0.01∗ | 0.984 | 0.679–1.424 | 0.93 |
| Waist circumference (cm) | 1.08 | 1.032–1.132 | 0.001∗∗ | 1.052 | 0.991–1.116 | 0.095 |
| HDL | 0.213 | 0.054–0.830 | 0.026∗ | 0.502 | 0.106–2.367 | 0.383 |
| TG | 1.379 | 0.95–2.003 | 0.091 | NA | ||
| Cumulative sum of risk factors for Mets | ||||||
| 5 component risk factors | 3.385 | 1.310–8.752 | 0.012∗ | 3.13 | 1.21–8.14 | 0.019∗ |
| Metabolic syndrome | 3.437 | 1.599–7.389 | 0.002∗∗ | 0.991 | 0.332–2.961 | 0.987 |
| Insulin resistance (HOMA-IR) | ||||||
| Continuous | 2.277 | 1.64–3.17 | < 0.001∗∗ | 2.069 | 1.266–3.382 | 0.004∗∗ |
| Dichotomized (HOMA-IR > 2.6) | 6.89 | 3.05–15.58 | < 0.001∗∗ | 3.26 | 1.07–9.91 | 0.037∗ |
The model is adjusted for age, postoperative pneumonia, and the other metabolic risk factors. ∗p < 0.05; ∗∗p < 0.01; OR, Odds Ratio; CI, confidence interval.