Table 3.
The reported prevalence and odds ratio of OSA in MCI population in included studies
| Author | Groups | Total sample | Subjects with OSA, n | Prevalence % (95% CI) | Odds Ratio (95% CI) | P-value |
|---|---|---|---|---|---|---|
| Dlugaj et al. [24] | MCI | 230 | 61 | 27 (21.0–32.8) | 1.03 (0.74–1.45) | 0.84 |
| aMCI | 120 | 32 | 52 (39.4–65.2) | |||
| naMCI | 110 | 29 | 48 (34.8–60.6) | |||
| Controls | 676 | 174a | 26 (22.5–29.2) | |||
| Guarnieri et al. [26] | MCI | 138 | 81 | 59 (50.0–66.9) | – | – |
| aMCI | NR | NR | – | |||
| naMCI | ||||||
| Controls | – | – | – | |||
| Kim et al. [27] | MCI | 30 | 21 | 70 (50.4–84.6) | 1.00 (0.33–3.02) | 1.00 |
| aMCI | NR | NR | – | |||
| naMCI | ||||||
| Controls | 30 | 21 | 70 (50.4–84.6) | |||
| aOsorio et al. [2] | MCI | 402 | 44 | 11 (8.2–14.5) | 3.61 (2.09–6.22) | < 0.0001 |
| aMCI | 402 | 44 | 100 (90–100) | |||
| naMCI | – | – | – | |||
| Controls | 607 | 23 | 4 (2.5–5.7) | |||
| Wilson et al. [28] | MCI | 37 | 17/24b | 71 (48.8–86.6) | 1.14 (0.34–3.86) | 0.83 |
| aMCI | 10 | NR | – | |||
| naMCI | 27 | |||||
| Controls | 37 | 17/25b | 68 (46.5–84.3) |
Abbreviations: CI confidence interval, MCI mild cognitive impairment, aMCI amnestic mild cognitive impairment, naMCI non-amnestic mild cognitive impairment, OSA obstructive sleep apnea
aData provided by study authors
bAHI data was available on 24 out of the 37 subjects with MCI and 25 out of the 37 control subjects