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. 2019 Aug 15;5:20. doi: 10.1186/s40813-019-0127-8

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Immunization and sampling schedule for second field trial. a. Standard vaccination scheme (2 applications), Porcilis® ColiClos ad us. vet. (Group 1.1). b. Adapted vaccination scheme (3 applications), Porcilis® ColiClos ad us. vet. (Group 1.2). c. Standard vaccination scheme (2 applications), Suisen ad us. vet. (Group 2.1). d. Adapted vaccination scheme (3 applications), Suisen ad us. vet. (Group 2.2). Timeline of sample collection in the vaccination trial; T0: before vaccination, 3 or 4 weeks ante insemination (a. i.), T1: 5 or 6 weeks ante-partum, T2: 2 or 3 weeks ante-partum, T3: at farrowing, P: 2 to 3 days postpartum (p.p.); T: blood sample of the sow, Col: colostrum, P: blood samples of piglets, NaCl injections were performed to achieve even numbers of injections between all groups