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Costunolide blocks aerobic glycolysis in HSCs. Primary rat HSCs at passages 3 through 5 were treated with costunolide at the indicated concentrations for 24 h. a – Measurement of glucose uptake using absorbance at 570/610 nm. b – Measurement of glucose consumption represented by GOD activity. c – Measurement of intracellular lactate levels. Statistics: *p < 0.05, **p < 0.01 vs. control
