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. 2019 Aug 15;20:652. doi: 10.1186/s12864-019-5979-4

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Metabolic consumption/production predictions S-GPR vs GPR. Percentage of improvement in predicting reaction activity in each method using S-GPR compared with GPR. Significance tested with Fisher’s Exact test [23] with p < 0.05 in all the analyses