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. 2019 Aug 15;20:652. doi: 10.1186/s12864-019-5979-4

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Pathways over-activation predicted in each method. Bars represent the % of pathway over-activity in Aldrin-exposed cells compared with non-exposed cells (n° of active reactions in Aldrin-exposed cells/n° of active reactions in non-exposed cells). The non-continuous bars indicate that a given pathway is predicted to be active only in Aldrin-exposed cells. Its significance was tested with a t-test [28] (p-value < 0.05)