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. 2019 Aug 14;10:254. doi: 10.1186/s13287-019-1350-6

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Scaffolds encapsulating BMP-hBMSCs showed much higher ALP activity and OCN deposition in the matrix. a ALP staining of the constructs in the Protein and Gene groups after 14 days of culture. The purple staining indicated the presence of ALP. b OCN deposition was detected by IHC in both groups after 14 days of culture. The brown staining, indicated by arrows, indicates OCN-positive deposition. Bar = 100 μm