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. 2019 Aug 14;10:254. doi: 10.1186/s13287-019-1350-6

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 5 — Constructs laden with lentiviral BMP-2-transduced hBMSCs were stiffer and had more calcium deposition after 56 days of implantation in vivo. a Macroscopic images showed new tissue formation in the Gene group construct. Scale = 1 mm, whereas those from the Protein Group remained morphologically unchanged. b Stiffness test. Maximum peak force was considerably higher in the Gene group constructs. (n = 3). c Total calcium content in the constructs. Again, the Gene group showed considerably higher calcium accumulation. (n = 3)