Table 4.
Diagnoses and hospitalization outcomes of newborns treated for risk of congenital syphilis
| RPRa Reactiveb | RPRa Non-reactivec | p-value | |||
|---|---|---|---|---|---|
| N=89 | (%) | N=111 | (%) | ||
| Discharge Diagnosesd | |||||
| None | 65 | (73) | 82 | (74) | NS |
| Sepsis | 8 | (7) | 2 | (2) | 0.02* |
| Perinatal asphyxia | 4 | (4) | 7 | (8) | NS* |
| Premature/low birth weight | 3 | (3) | 3 | (3) | NS* |
| Antibiotic prophylaxis (well baby)e | 9 | (8) | 15 | (17) | NS |
| HIV Exposure | 4 | (4) | 9 | (10) | NS |
| Number of diagnoses | |||||
| None | 65 | (73) | 82 | (74) | NS |
| One diagnosis | 20 | (22) | 22 | (20) | NS |
| Two diagnoses | 4 | (5) | 7 | (6) | NS* |
| Disposition | |||||
| Discharged | 79 | (89) | 107 | (96) | 0.05 |
| Transferred | 2 | (2) | 0 | (0) | NS* |
| Dead | 2 | (2) | 1 | (1) | NS* |
| Left against medical advice | 6 | (7) | 3 | (3) | NS* |
X2 test used for all comparisons except where indicated as (*) Fisher’s exact test
Neonatal treatment was based on Maternal RPR Results at MSF Castors Maternity Hospital from March 2017 to February 2018
aRPR Rapid plasma reagin test b RPR reactive = titre > 1:4c RPR non-reactive = titre of 1:2
dSum of n for discharge diagnoses is not equal to 100% as patients can present with more than one diagnosis
NS = Not significant
eAntibiotic prophylaxis = infants who are treated for a minimum of 48 h of antibiotics based on maternal and birth risk factors but who are otherwise well