Table 1.
Characteristics of the total cohort also split by ISAR and CGA results
| Total (n = 547) | ISAR- (n = 229; 41.9%) | ISAR+/CGA normal (n = 145; 26.5%) | ISAR+/CGA abnormal (n = 97; 17.7%) | p-value ISAR+/CGA normal vs ISAR- | p-value ISAR+/CGA abnormal vs ISAR- | p-value ISAR+/CGA abnormal vs ISAR+/CGA normal | |
|---|---|---|---|---|---|---|---|
| Age (years) | 78.1 ± 6.0 | 77.9 ± 5.4 | 77.0 ± 5.9 | 80.5 ± 6.5 | 0.259 | 0.001 | <0.001 |
| Sex (male) | 299 (54.7) | 122 (53.3) | 96 (66.2) | 43 (44.3) | 0.013 | 0.118 | <0.001 |
| Anemia | 152 (27.8) | 55 (24.0) | 51 (35.2) | 29 (29.9) | 0.019 | 0.336 | 0.318 |
| Chronic kidney disease | 240 (43.9) | 86 (37.6) | 75 (51.7) | 43 (44.3) | 0.007 | 0.327 | 0.194 |
| Heart failure | 106 (19.4) | 39 (17.0) | 35 (24.1) | 16 (16.5) | 0.140 | 0.999 | 0.263 |
| Coronary heart disease | 213 (38.9) | 90 (39.3) | 51 (35.2) | 45 (46.4) | 0.511 | 0.329 | 0.142 |
| Atrial fibrillation | 174 (31.8) | 62 (27.1) | 47 (32.4) | 37 (38.1) | 0.293 | 0.050 | 0.412 |
| Other cardiac arrhythmias | 70 (12.8) | 23 (10.0) | 18 (12.4) | 17 (17.5) | 0.498 | 0.097 | 0.354 |
| Valve insufficiency | 196 (35.8) | 78 (34.1) | 53 (36.6) | 39 (40.2) | 0.738 | 0.213 | 0.423 |
| Chronic obstructive pulmonary disease | 69 (12.6) | 25 (10.9) | 17 (11.7) | 15 (15.5) | 0.867 | 0.277 | 0.448 |
| Peripheral artery disease | 76 (13.9) | 27 (11.8) | 22 (15.2) | 21 (21.6) | 0.348 | 0.040 | 0.237 |
| Arterial hypertension | 430 (78.6) | 175 (76.4) | 113 (77.9) | 80 (82.5) | 0.704 | 0.311 | 0.626 |
| Diabetes | 171 (31.3) | 71 (31.0) | 45 (31.0) | 33 (34.0) | 0.999 | 0.606 | 0.676 |
| Hyperlipoproteinemia | 269 (49.2) | 96 (41.9) | 79 (54.5) | 55 (56.7) | 0.025 | 0.011 | 0.694 |
| Nicotine abuse | 82 (15.0) | 34 (14.8) | 25 (17.2) | 11 (11.3) | 0.561 | 0.484 | 0.202 |
| Obesity | 116 (21.2) | 46 (20.1) | 29 (20.0) | 23 (23.7) | 0.999 | 0.463 | 0.427 |
| History of myocardial infarction | 56 (10.2) | 23 (10.0) | 9 (6.2) | 13 (13.4) | 0.255 | 0.443 | 0.073 |
| History of pulmonary embolism | 11 (2.0) | 2 (0.9) | 4 (2.8) | 3 (3.1) | 0.378 | 0.070 | 0.447 |
| History of stroke | 56 (10.2) | 14 (6.1) | 16 (11.0) | 15 (15.5) | 0.116 | 0.006 | 0.255 |
| History of thrombosis | 49 (9.0) | 19 (8.3) | 10 (6.9) | 12 (12.4) | 0.695 | 0.306 | 0.179 |
| Hyperthyroidism | 24 (4.4) | 15 (6.6) | 1 (0.7) | 5 (5.2) | 0.007 | 0.802 | 0.042 |
| Hypothyroidism | 84 (15.4) | 30 (13.1) | 30 (20.7) | 11 (11.3) | 0.081 | 0.859 | 0.118 |
| Dementia | 37 (6.8) | 4 (1.7) | 9 (6.2) | 16 (16.5) | 0.067 | <0.001 | 0.005 |
| Alcohol abuse | 19 (3.5) | 6 (2.6) | 7 (4.8) | 2 (2.1) | 0.261 | 0.999 | 0.317 |
| Depression | 30 (5.5) | 9 (3.9) | 5 (3.4) | 7 (7.2) | 0.999 | 0.265 | 0.236 |
| Anxiety disorder | 2 (0.4) | 1 (0.4) | 0 (0.0) | 0 (0.0) | 0.999 | 0.999 | 0.999 |
| Parkinson’s disease | 6 (1.1) | 3 (1.3) | 2 (1.4) | 0 (0.0) | 0.999 | 0.557 | 0.515 |
| Polyneuropathy | 40 (7.3) | 13 (5.7) | 10 (6.9) | 14 (14.4) | 0.825 | 0.009 | 0.028 |
| Cancer | 215 (39.3) | 89 (38.9) | 73 (50.3) | 21 (21.6) | 0.041 | 0.003 | <0.001 |
| Cataract | 33 (6.0) | 8 (3.5) | 13 (9.0) | 6 (6.2) | 0.036 | 0.371 | 0.472 |
| Presbycusis | 21 (3.8) | 8 (3.5) | 4 (2.8) | 7 (7.2) | 0.773 | 0.161 | 0.128 |
| Anal incontinence | 3 (0.5) | 1 (0.4) | 2 (1.4) | 0 (0.0) | 0.562 | 0.999 | 0.515 |
| Urinary incontinence | 4 (0.7) | 1 (0.4) | 0 (0.0) | 2 (2.1) | 0.999 | 0.218 | 0.165 |
| Pressure ulcers | 24 (4.4) | 1 (0.4) | 4 (2.8) | 14 (14.4) | 0.075 | <0.001 | 0.002 |
| Rheumatism | 24 (4.4) | 11 (4.8) | 5 (3.4) | 4 (4.1) | 0.609 | 0.999 | 0.999 |
CGA, comprehensive geriatric assessment; ISAR, Identification of Seniors at Risk; ISAR+, positive ISAR screening (score ≥ 2); ISAR-, negative ISAR screening (score < 2); CGA abnormal, impairment of ADL plus another domain of the CGA. In 318 ISAR+ patients, 242 CGAs were performed (76 missing due to transfer, discharge, foreign-language or incompliance of patients). Boldface values were significant at p <=0.05