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. 2019 Aug 14;19:184. doi: 10.1186/s12886-019-1196-9

Table 4.

Comparison of total hemorrhage area, hemorrhage lesion number, maximum hemorrhage area, total exudation area, exudation lesion number, and maximum exudation area among different DR stages

Dependent variable Group Mean difference Standard error P 95% Confidence Interval
Lower limit Upper limit
Hemorrhage area aGroup 1 aGroup 2 −14,297.535* 3042.766 < 0.001 −20,344.39 − 8250.68
aGroup 3 −15,558.166* 3262.459 < 0.001 −22,041.62 − 9074.71
Group 2 Group 1 14,297.535* 3042.766 < 0.001 8250.68 20,344.39
Group 3 − 1260.631 3464.848 .717 − 8146.29 5625.03
Group 3 Group 1 15,558.166* 3262.459 < 0.001 9074.71 22,041.62
Group 2 1260.631 3464.848 .717 − 5625.03 8146.29
Hemorrhage lesion number Group 1 Group 2 −23.364* 2.721 < 0.001 −28.77 −17.96
Group 3 −8.091* 2.918 .007 −13.89 −2.29
Group 2 Group 1 23.364* 2.721 < 0.001 17.96 28.77
Group 3 15.273* 3.099 < 0.001 9.11 21.43
Group 3 Group 1 8.091* 2.918 .007 2.29 13.89
Group 2 −15.273* 3.099 < 0.001 −21.43 −9.11
Maximum hemorrhage area Group 1 Group 2 − 2959.526* 1039.915 .006 − 5026.14 − 892.91
Group 3 − 6497.670* 1114.998 < 0.001 − 8713.49 − 4281.85
Group 2 Group 1 2959.526* 1039.915 .006 892.91 5026.14
Group 3 − 3538.144* 1184.168 .004 − 5891.43 − 1184.86
Group 3 Group 1 6497.670* 1114.998 < 0.001 4281.85 8713.49
Group 2 3538.144* 1184.168 .004 1184.86 5891.43
Exudation area Group 1 Group 2 − 5093.435 2754.178 .068 −10,566.79 379.92
Group 3 −13,566.408* 2953.034 < 0.001 −19,434.94 − 7697.87
Group 2 Group 1 5093.435 2754.178 .068 − 379.92 10,566.79
Group 3 − 8472.973* 3136.228 .008 −14,705.57 − 2240.38
Group 3 Group 1 13,566.408* 2953.034 < 0.001 7697.87 19,434.94
Group 2 8472.973* 3136.228 .008 2240.38 14,705.57
Exudation lesion number Group 1 Group 2 −14.655* 4.399 .001 −23.40 −5.91
Group 3 −5.957 4.716 .210 −15.33 3.42
Group 2 Group 1 14.655* 4.399 .001 5.91 23.40
Group 3 8.699 5.009 .086 −1.26 18.65
Group 3 Group 1 5.957 4.716 .210 −3.42 15.33
Group 2 −8.699 5.009 .086 −18.65 1.26
Maximum exudation area Group 1 Group 2 − 1043.818 1131.248 .359 − 3291.94 1204.30
Group 3 − 6505.911* 1212.926 < 0.001 − 8916.35 − 4095.48
Group 2 Group 1 1043.818 1131.248 .359 − 1204.30 3291.94
Group 3 − 5462.093* 1288.171 < 0.001 − 8022.06 − 2902.12
Group 3 Group 1 6505.911* 1212.926 < 0.001 4095.48 8916.35
Group 2 5462.093* 1288.171 < 0.001 2902.12 8022.06

*p < 0.05

a Group 1, mild NPDR and moderate NPDR; group 2, severe NPDR; group 3, PDR