Table 3.
The effect of clinicopathologic factor and UNC13C expression on mortality density and adjusted hazard ratio (aHR) among OSCC patients.
| Factors | No. of patient | Follow-up (person-year) | No. of death | Mortality densitya | aHRb | (95% CI) | Interaction P-value |
|---|---|---|---|---|---|---|---|
| Overall Mortality From Primary Malignancy To Death | |||||||
| T classification | |||||||
| I/II | 152 | 905.32 | 52 | 5.7 | 1 | ||
| III/IV | 116 | 498.87 | 65 | 13.0 | 2.1 | (1.4–3.0) | 0.0001 |
| N classification | |||||||
| N0/N1 | 206 | 1248.94 | 73 | 5.8 | 1 | ||
| N2/N3 | 62 | 155.25 | 44 | 28.3 | 3.1 | (2.1–4.6) | <0.0001 |
| AJCC tumor stage | |||||||
| I/II | 109 | 731.57 | 30 | 4.1 | 1 | ||
| III/IV | 159 | 672.62 | 87 | 12.9 | 2.7 | (1.7–4.3) | <0.0001 |
| Tumor differentiation | |||||||
| Well | 42 | 277.29 | 9 | 3.2 | 1 | ||
| Moderate/poor | 226 | 1126.89 | 108 | 9.6 | 2.9 | (1.4–6.1) | 0.0037 |
| UNC13C expression | |||||||
| Low | 190 | 1025.45 | 83 | 8.1 | 1 | ||
| High | 67 | 349.61 | 19 | 5.4 | 0.59 | (0.35–0.95) | 0.0377 |
a
Mortality density was displayed as per 100 people-years.
b
aHR was adjusted for gender and age.