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. 2019 Aug 8;10:715. doi: 10.3389/fgene.2019.00715

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Copyright © 2019 Liu, Yu, Dong, Zhao, Liu, Zhang, Li, Du and Cheng

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A) The preferences for the amino acids around the calpain cleavage sites and non-calpain cleavage sites. (B–C) Comparison of the surface accessibility (B) and disorder information between calpain cleavage sites and non-calpain cleavage sites. (D) The 4-, 6-, 8-, and 10-fold cross-validations results for calpain. (E–G) Comparison of the models of calpain (E), µ-calpain (F), and m-calpain (G) with the existing tools, and the dots were the Sn and Sp values adopted from the related literatures.