Figure 2.

Illustrates the platelets ability to aggregate in response to stimulation by three different agonists. Platelet aggregation was measured during support with extracorporeal membrane oxygenation (ECMO) and compared with healthy controls. Agonists used to stimulate platelet aggregation: (A) ADP, Adenosine diphosphate; (C) AA, arachidonic acid; and (B) TRAP, thrombin receptor activating peptide-6. The bars indicate mean with standard deviation. An X-mark in the circle indicates that the patient has received platelet concentrate within 24 h prior to blood sampling. To illustrate the association between platelet aggregation and platelet count, patients with platelet counts below 50 × 10⁹ /L are marked red. Due to practical reasons, platelet aggregation on day 2 was not measured in 2 patients.