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. 2019 Aug 8;10:1742. doi: 10.3389/fmicb.2019.01742

Table 1.

SNPs above the prevalence filter (>15%/<85%).

UniProt BLAST annotation General information PROVEAN GO term
Protein name UniProt acc. no. Prevalence Variant Prediction no. Aspect Info
Phospho-N-acetylmuramoyl-pentapeptide- transferase A0A220PD53 19.0% V340G Deleterious
Undecaprenyldiphospho- muramoylpentapeptide beta-N-acetylglucosaminyltransferase A0A220PD36 20.7% T148A Neutral
Dienelactone hydrolase family protein A0A1Y0GE31 19.0% GO:0016787 F hydrolase activity
Type VI secretion system Vgr family protein A0A1G5LY91 19.0% Q591L Deleterious
Uncharacterized protein A0A1C7C392 20.7%
Putative allantoin permease A0A0P1D6C1 15.5% F393L Neutral GO:0005215 F Transporter activity
GO:0055085 P Transmembrane transport
Putative aldose 1-epimerase A0A220PGB1 15.5% Q268H Deleterious
ATP synthase epsilon chain Q9HT21 15.5% G67A Deleterious GO:0046933 F Proton-transporting ATP synthase activity, rotational mechanism
GO:0015986 P ATP synthesis coupled proton transport
Uncharacterized protein A0A1G5M0Q6 15.5% T106P Neutral
Integrase A0A220P6P1 20.7% K219N Neutral
Acyl-[acyl-carrier-protein]–UDP-N- acetylglucosamine O-acyltransferase Q9X6P4 15.5% Q100E Deleterious GO:0008780 F Acyl-[acyl-carrier-protein]-UDP-N-acetyl- glucosamine O-acyltransferase activity
GO:0009245 P Lipid A biosynthetic process
GO:0009103 P Lipopolysaccharide biosynthetic process
Putative transcriptional regulator A0A220PB10 17.2% L269S Neutral
Phosphotransferase family protein A0A220PAS8 20.7% Q221* Neutral
Type VI secretion system Vgr family protein A0A1G5KZC8 19.0% M411R Deleterious
Uncharacterized protein A0A1D5BW36 20.7% N165D Neutral GO:0000155 F Phosphorelay sensor kinase activity
MexZ Q9ZH26 19.0% L123* Deleterious GO:0003677 F DNA binding
GO:0006355 P Regulation of transcription, DNA-templated
GO:0006351 P Transcription, DNA-templated
MerR family transcriptional regulator A0A1S1BX29 15.5% A115T Deleterious GO:0003677 F DNA binding
GO:0006355 P Regulation of transcription, DNA-templated
Uncharacterized protein A0A220PHL6 17.2%
Uncharacterized protein A0A220PHL6 17.2%

Cluster 2: 19 SNPs.

Only SNPs above the prevalence filter (prevalence in at least 15% of strains) and with resulting change in coded amino acid are reported, i.e., SNPs not resulting in amino acid change (non-coding SNPs) are omitted from this table. Variant annotation was performed by SnpEff. Protein function prediction was performed by PROVEAN protein with a default cutoff of −2.5. If variant is not coding, information about “variant” (general information) and “prediction” (PROVEAN) is not indicated in the table.

UniProt BLAST annotation: the best hit (by identity) is given in the table.

Bold print: Proteins discussed in the manuscript text.

*

(asterisk) = translation termination (stop) codon.

UniProt acc. no., UniProt accession number; no., number.