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. 2019 Aug 8;10:1904. doi: 10.3389/fimmu.2019.01904

Figure 5.

Figure 5

Depletion of AGER protects against septic shock. (A) Survival of indicated mice primed with poly(I:C) (10 mg/kg, i.p.) and then challenged 6 h later with LPS (2 mg/kg, i.p.). n = 10 mice/group, *P < 0.05, Kaplan-Meier survival analysis. (B,C) In parallel to panel A, quantitation of indicated serum markers (B) or hematoxylin/eosin staining of indicated tissues (C) in poly(I:C)-primed mice challenged with LPS at +3 h (bar = 100 μM). n = 5 mice/group, *P < 0.05, ANOVA LSD test. Animal data represent two independent experiments.