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. 2019 Aug 13;93(17):e00599-19. doi: 10.1128/JVI.00599-19

FIG 6.

FIG 6

Treated particle expansion and unmodeled cryoEM density. (A) Atomic model of control E1 seen along 2-fold axis. (B) Atomic model of the treated intermediate virion seen along 2-fold axis showing opening between two VP2 helices. (C) Unmodeled cryoEM density of control E1 (gray isosurface). Inset shows unmodeled density at the 3-fold axis. Red arrows indicate N termini of VP2 (Cys 7) in the vicinity of unmodeled density blob. Triangle indicates 3-fold symmetry axis. (D) Unmodeled cryoEM density of the treated virion (gray isosurface). Inset shows unmodeled density spanning the capsid near 2-fold axis. Red arrows indicate N termini of VP1 (Asn 55) in the vicinity of the unmodeled density spanning the capsid. Pentagon and oval indicate 5-fold and 2-fold symmetry axes, respectively. For panels A to D: VP1 (blue), VP2 (cyan), VP3 (green), VP4 (yellow), lipid factor (orange).