TABLE 3.
Amino acid mutations of K09 after the IY7640 treatment
| Expt | Clone | Escape mutation(s) identified in K09 proteina
|
|||
|---|---|---|---|---|---|
| PB2 | HA | NP | NA | ||
| 1 | 1 | − | L49I, E447K | N492K, E494G | − |
| 2 | − | L49I, E447K | − | − | |
| 3 | − | L49I, E447K | − | Q45L | |
| 2 | 1 | E208A | M403T | − | − |
| 2 | − | P229S, M403T | − | K347R | |
| 3 | − | M403T | − | − | |
−, no genetic mutations from two independent experiments.