TABLE 4.
EC50 values of IY7640 escape mutant viruses
| Virus | EC50 (μM) of IY7640 |
|
|---|---|---|
| CPE assay | Plaque reduction assay | |
| rK09 | 1.95 | 1.58 |
| rK09/HA:L49I | 15.4 | 16.3 |
| rK09/HA:M403T | 116 | 445.8 |
| rK09/HA:E447K | 207.1 | 971.8 |
| rK09/HA:L49I+E447K | 69.46 | 767 |
EC50 values of IY7640 escape mutant viruses
| Virus | EC50 (μM) of IY7640 |
|
|---|---|---|
| CPE assay | Plaque reduction assay | |
| rK09 | 1.95 | 1.58 |
| rK09/HA:L49I | 15.4 | 16.3 |
| rK09/HA:M403T | 116 | 445.8 |
| rK09/HA:E447K | 207.1 | 971.8 |
| rK09/HA:L49I+E447K | 69.46 | 767 |