Table 3.
Antimicrobial activities of novel metal complexes of 2-amino-4-substituted phenylthiazole Schiff bases against different microbial strains (mean ± S.D.).
| Compounds |
Bacterial strain |
Fungal strain |
|||
|---|---|---|---|---|---|
| E. coli (res) | K. pneumoniae | S. aureus (res) | C. albicans | C. neoformans | |
| 4e | 15.83 ± 1.47∗ | 15.17 ± 2.14 | 16.17 ± 2.04∗ | 10.17 ± 1.84 | 12.5 ± 1.52 |
| 5a(Lig) | 13.67 ± 2.34 | 12.67 ± 2.25 | 15.83 ± 2.79∗ | 12.17 ± 2.23 | 13.33 ± 1.37 |
| 5b(Lig) | 15.33 ± 2.07 | 13.5 ± 2.43 | 11.5 ± 1.87 | 12 ± 1.27 | 12.33 ± 1.75 |
| 6a | 16.67 ± 2.34∗ | 16.17 ± 1.94∗ | 20.83 ± 1.84∗ | 12.83 ± 2.23 | 13.67 ± 2.94 |
| 6b | 15.83 ± 1.84∗ | 16 ± 2.37∗ | 18.33 ± 1.75∗ | 13.33 ± 2.34 | 12.67 ± 1.51 |
| 6c | – | 14.67 ± 3.14 | 14.83 ± 1.84 | 11.33 ± 1.51 | 15.83 ± 1.84 |
| 6d | 15.5 ± 3.21∗ | 16.17 ± 2.99∗ | 16.83 ± 2.71∗ | 12.67 ± 2.34 | 12.17 ± 2.71 |
| 6e | 14.83 ± 2.56 | 15.83 ± 2.23 | 14.5 ± 1.52 | 11.17 ± 6.21 | 10.5 ± 1.52 |
| 6f | – | 16.67 ± 1.37∗ | 15.17 ± 1.94 | 12.5 ± 1.52 | 10.33 ± 1.75 |
| RA | 12.67 ± 1.51 | 15.33 ± 1.97 | 13 ± 1.67 | 19.33 ± 4.68 | 24.17 ± 1.94 |
| RA1 | – | 15.09 ± 1.13 | – | ||
Results expressed in Mean ± S.D. (n = 6), The data were analysed by One Way ANOVA followed by Dunnett's Post Hoc test, (statistical significance at *p < 0.05 in comparison to reference antibiotic (RA): amoxicillin (antibacterial), fluconazole (antifungal) and RA1: ampicillin (antibacterial); -, no zone of inhibition.