Table 3.
Simple Logistic Regression on associated factors with development of hypothyroidism post RAI therapy.
| Independent variable | Non-hypothyroid | Hypothyroid | Regression coefficient (β) | Crude odds ratio (95% CI) | Wald statistic (df) | p-value |
|---|---|---|---|---|---|---|
| Age | 46.77 ± 11.80 | 48.67 ± 12.25 | 0.01 | 1.013 (0.957–1.017) | 0.761 (1) | 0.385 |
| Sex | ||||||
| Female | 67 (74.5) | 20 (44.4) | −0.76 | 0.466 (0.221–0.984) | 4.014 (1) | 0.045 |
| Male | 25 (25.5) | 25 (55.6) | 0.00 | 1 | ||
| Race | ||||||
| Malay | 85 (92.4) | 41 (91.1) | −0.169 | 0.844 (0.234–3.047) | 0.067 (1) | 0.796 |
| Chinese | 7 (7.6) | 4 (8.9) | 0.00 | 1 | ||
| Aetiology of hyperthyroidism | ||||||
| Graves' disease | 42 (45.7) | 23 (51.1) | −0.05 | 0.951 (0.445–2.033) | 0.017 (1) | 0.897 |
| Non Graves' disease | 50 (54.3) | 22 (48.9) | −1.18 | 0.307 (0.790–1.183) | 2.943 (1) | 0.086 |
| Unclassified | 63 (68.5) | 29 (64.4) | 0.00 | 1 | 0.223 (1) | 0.637 |
| Dose of RAI | ||||||
| ≤10 mci | 29 (31.5) | 16 (35.6) | 0.18 | 1.199 (0.565–2.543) | ||
| >10 mCi | 0.00 | 1 | ||||
| Antithyroid drug post RAI | ||||||
| Yes | 78 (84.8) | 24 (53.3) | −1.58 | 0.205 (0.091–0.450) | 14.461 (1) | <0.001 |
| No | 14 (15.2) | 21 (46.7) | 0.00 | 1 | ||