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. 2019 Aug 15;14(8):e0220577. doi: 10.1371/journal.pone.0220577

Table 1. Gene expression profile of THP-1 derived macrophages cultivated in hyperglycemia and hypoxia.

Symbol Entrez Gene Name Fold Change
TNF-α Pro-inflammatory cytokines Tumour necrosis factor alpha 3.50
IL-1A Pro-inflammatory cytokines interleukin 1 alpha 6.82
IL-1B Pro-inflammatory cytokines interleukin 1 beta 2.30
IL-6 Pro-inflammatory cytokines interleukin 6 6.49
CSF2 Pro-inflammatory cytokines colony stimulating factor 2 (GM-CSF) 6.49
IL-24 Pro-inflammatory cytokines interleukin 24 4.00
LIF Pro-inflammatory cytokines interleukin 6 family cytokine 4.32
CXCL1 Chemokines C-X-C motif chemokine ligand 1 3.73
CXCL2 Chemokines C-X-C motif chemokine ligand 2 2.56
CXCL3 Chemokines C-X-C motif chemokine ligand 3 1.94
CXCL4 Chemokines C-X-C motif chemokine ligand 4 1.98
CXCL5 Chemokines C-X-C motif chemokine ligand 5 4.56
CCL4 Chemokines C-C motif chemokine ligand 4 2.68
CCL19 Chemokines C-C motif chemokine ligand 19 2.17
TGF-β1 Wound healing cytokine Transforming growth factor beta 1 -2.01
CD-36 Phagocytosis CD36 molecule -1.96
SCARB-1 Phagocytosis Scavenger receptor class B member 1 -2.47