Figure 1.

A diagram of the inclusions/exclusions by round of screening. A positive co-test was a positive HPV test and/or a positive cytology (ASC-US or more severe cytology) and a negative co-test was a negative HPV test and negative cytology. The gray-shaded boxes indicate the study groups of the first, second, third, and fourth positive co-tests following 0–3 consecutive negative co-tests, respectively. AGC = atypical glandular cells; ASC-H = atypical squamous cells, cannot rule out HSIL; ASC-US = atypical squamous cells of undetermined significance; CIN2 = cervical intraepithelial neoplasia grade 2 or more severe diagnoses (CIN2+); HPV = human papillomavirus; HSIL+ = high-grade squamous intraepithelial lesion (HSIL) or more severe; LSIL = low-grade squamous intraepithelial lesion.