Table 5.
Estimated excess relative risk (ERR) of smoking-related lung cancer by histologic cell-types and race/ethnicity*
| Smoking level | African American ERR (95% CI) | Native Hawaiian ERR (95% CI) | Latino ERR (95% CI) | Japanese American ERR (95% CI) | White ERR (95% CI) |
|---|---|---|---|---|---|
| After accumulation of 25 pack-years at 10 CPD | |||||
| All lung cancers | 19.1 (16.9 to 21.3) | 21.9 (18.0 to 25.8) | 8.0 (6.6 to 9.4) | 10.1 (8.5 to 11.7) | 11.9 (10.0 to 13.8) |
| Adenocarcinoma | 8.3 (6.7 to 9.9) | 9.6 (6.6 to 12.6) | 2.8 (1.8 to 3.8) | 5.7 (4.3 to 7.1) | 5.7 (4.2 to 7.2) |
| Squamous cell | 77.8 (51.3 to 104.3) | 80.7 (44.6 to 116.8) | 31.4 (18.4 to 44.4) | 36.5 (21.4 to 51.5) | 42.4 (25.1 to 59.7) |
| Small cell | 104.2 (43.4 to 164.9) | 191.8 (67.5 to 316.1) | 59.4 (21.4 to 97.4) | 59.9 (20.1 to 99.7) | 76.7 (27.1 to 126.3) |
| Large cell | 75.6 (21.9 to 129.3) | 25.1 (-8.0 to 58.2) | 33.2 (5.0 to 61.4) | 14.4 (-1.9 to 30.7) | 26.9 (1.4 to 52.4) |
| After accumulation of 50 pack-years at 20 CPD | |||||
| All lung cancers | 31.7 (28.1 to 35.3) | 35.3 (30.5 to 40.1) | 20.0 (17.1 to 22.9) | 21.4 (16.0 to 23.8) | 24.0 (21.5 to 26.5) |
| Adenocarcinoma | 14.3 (11.7 to 16.9) | 14.7 (11.3 to 18.1) | 6.9 (5.0 to 8.8) | 9.3 (7.6 to 11.0) | 11.5 (11.2 to 12.4) |
| Squamous cell | 134.2 (88.5 to 179.9) | 142.6 (89.5 to 195.7) | 77.8 (47.8 to 107.8) | 91.9 (60.7 to 123.1) | 86.3 (57.3 to 115.3) |
| Small cell | 160.3 (65.4 to 255.2) | 365 (153.3 to 576.7) | 131.7 (49.6 to 213.8) | 144 (61.1 to 226.9) | 160.6 (69.9 to 251.3) |
| Large cell | 96.2 (24.7 to 167.7) | 33.8 (-3.4 to 71.1) | 85.2 (18.6 to 151.8) | 54.7 (12.8 to 96.6) | 38.8 (8.4 to 69.2) |
*
CI = confidence interval; CPD = cigarettes per day; ERR =excess relative risk.