Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 Aug 15;9:11918. doi: 10.1038/s41598-019-48427-3

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Multiple ultrasonography (US) parameters measured in the two groups of mice using a VisualSonic VEVO2100, with mice lightly anesthetized under isofluorane, 6 months after pregnancy. Mice were treated with dobutamine (mimicking an effort stress [see Material and Methods]) or not. Parameters were evaluated by Doppler US and direct measures for geometrical parameters of the heart. Graphs represent the normalized levels for each group, the control group without dobutamine was the reference. Data are mean±SD analyzed by two-way ANOVA followed by Student-Neumann-Keuls post-hoc tests. The hash (#) and asterisk (*) symbols mark the dobutamine effect and the genotype effect (pathological pregnancy), respectively, with *^,# for p < 0.05, **^,## for p < 0.01 and ***^,### for p < 0.001. The “I” marks an interaction effect between the two parameters measured. In the graph, among 59 parameters measured, 20 with significant values are presented. The significance of the US abbreviations are given in Supplemental Table 1. In the figure, AoV_VTI_Mean_Vel, mean ascending aorta peak velocity; AoV_VTI_Mean_Grad, mean ascending aorta peak gradient; AoV_VTI_Peak_Vel, ascending aorta mean velocity; AoV_VTI_Peak_Grad, ascending aorta mean pressure gradient; AV_Peak_Vel, ascending aorta peak velocity; AV_Peak_Pressure, ascending aorta pressure gradient; PET, pulmonary artery ejection time; RVOT_VTI_Mean_Vel, pulmonary artery mean velocity; RVOT_VTI_Mean_Grad, pulmonary artery mean velocity gradient; RVOT_VTI_Peak_Vel, pulmonary artery peak velocity; RVOT_VTI_Peak_Grad, pulmonary artery peak velocity gradient; MV_A, mitral valve a wave peak velocity; LVID_s, left ventricle internal diameter, systole; LVID + PWd + IVSd, calculation of the sum of LV internal diameter, LV posterior wall thickness and interventricular septum thickness; EF, ejection fraction (extrapolated from M mode); FS, fractional shortening; LV_Mass_mg, LV mass; LV_Vol_s, telesystolic LV volume; ROv.PI, pulsatility index; Aortic flow, flow rate in the aorta.