Table 1.

Summary of gene pathways statistically enriched in the hearts 8 months post-pregnancy.

Gene Set	Description	Size	Expect	Ratio	P Value	FDR
Up-regulated genes
GO: Biological Process
GO:0070972	protein localization to endoplasmic reticulum	137	0.619	20.97	3.37e-14	2.86e-11
GO:0006413	translational initiation	192	0.868	14.96	2.67e-12	1.13e-9
GO:0014812	muscle cell migration	79	0.357	13.98	0	0.0034
GO:0006631	fatty acid metabolic process	357	1.615	4.333	0.001	0.095
GO:Celular Components
GO:0005840	ribosome	229	1.340	13.42	4.44e-16	7.63e-14
GO:0098798	mitochondrial protein complex	266	1.557	5.78	0	0.001
GO:0070469	respiratory chain	100	0.585	10.25	0	0.001
GO:0030055	cell-substrate junction	411	2.405	3.74	0.0006	0.016
Pathways
hsa03010 (K)	Ribosome	153	1.003	15.94	8.88e-16	2.89e-13
hsa00190 (K)	Oxidative phosphorylation	133	0.872	6.87	0.00020	0.019
hsa00980 (K)	Metabolism of xenobiotics by cytochrome P450	76	0.498	8.02	0.0015	0.069
hsa05418 (K)	Fluid shear stress and atherosclerosis	139	0.911	5.48	0.0021	0.074
WP477 (W)	Cytoplasmic Ribosomal Proteins	91	0.685	18.97	5.20e-14	2.28e-11
WP623 (W)	Oxidative phosphorylation	62	0.466	8.57	0.0011	0.12
Down-regulated genes
GO:Biological Process
GO:1901652	response to peptide	487	1.24	7.20	0.0000029	0.0025
GO:0006631	fatty acid metabolic process	357	0.91	7.64	0	0.0126
GO:0071887	leukocyte apoptotic process	107	0.27	14.56	0.00020	0.0334
GO:0022407	regulation of cell-cell adhesion	383	0.98	6.10	0.00040	0.0421
GO:0048545	response to steroid hormone	388	0.99	6.02	0.00040	0.0421
Pathways
WP619 (W)	Type II interferon signaling (IFNG)	37	0.14	40.50	4.6234e-9	0.0000020
R-HSA-877300 (R)	Interferon gamma signaling	92	0.27	18.50	0.0000064	0.011
hsa04621 (K)	NOD-like receptor signaling pathway	168	0.67	8.89	0	0.012
hsa04620 (K)	Toll-like receptor signaling pathway	104	0.41	9.57	0.00070	0.06