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. 2019 Aug 15;10:3686. doi: 10.1038/s41467-019-11642-7

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 6 — Protein corona of uncoated and pre-coated liposomes in patients’ plasma. a SDS-PAGE gel of human plasma proteins obtained from uncoated and pre-coated DOTAP liposomes following incubation in patients’ plasma at different time points. The molecular weights of the proteins in the standard ladder (MW) and the protein pattern of pre-coated liposomes (i.e., before incubation in patients’ plasma; labelled as PL) are reported in the middle for reference. b One-dimensional (1D) averaged protein profiles of coronas formed around uncoated and pre-coated DOTAP after exposure to patients’ plasma. c Residual obtained by subtracting the 1D profile of pre-coated from that of uncoated DOTAP