Table 2.
Short-term (10 years) cost-effectiveness analysis for lifestyle interventions among individuals with prediabetes.
| Intervention Type | |||
|---|---|---|---|
| DPP | DPP-YMCA | HELP-PD | |
| Age group | 55–65 yrs | ||
| Diabetes averted (1000 s) | 258.78 | 150.35 | 226.00 |
| Death averted (1000 s) | 18.24 | 4.96 | 22.80 |
| Gain in diabetes-free survival time (Years) | 0.03 | 0.02 | 0.03 |
| Intervention cost ($1000) | 31,074,700 | 7,677,100 | 10,039,300 |
| Aversion savings ($1000) | 22,048,056 | 12,809,820 | 19,255,200 |
| Total savings ($1000) | −9,026,644 | 5,132,720 | 9,215,900 |
| Age group | 45–65 yrs | ||
| Diabetes averted (1000 s) | 489.06 | 296.67 | 509.60 |
| Death averted (1000 s) | 44.08 | 26.35 | 58.00 |
| Gain in diabetes-free survival time (Years) | 0.06 | 0.03 | 0.06 |
| Intervention cost ($1000) | 62,174,800 | 15,361,400 | 20,088,000 |
| Aversion savings ($1000) | 41,667,912 | 25,276,284 | 43,417,920 |
| Total savings ($1000) | −20,506,888 | 9,914,884 | 23,329,920 |
| Age group | 35–65 yrs | ||
| Diabetes averted (1000 s) | 652.84 | 394.32 | 764.00 |
| Death averted (1000 s) | 77.14 | 44.95 | 107.60 |
| Gain in diabetes-free survival time (Years) | 0.07 | 0.05 | 0.08 |
| Intervention cost ($1000) | 92,405,900 | 22,829,300 | 29,853,700 |
| Aversion savings ($1000) | 55,621,968 | 33,596,064 | 65,092,800 |
| Total savings ($1000) | −36,783,932 | 10,766,764 | 35,239,100 |
| Age group | 25–65 yrs | ||
| Diabetes averted (1000 s) | 915.80 | 553.35 | 927.60 |
| Death averted (1000 s) | 83.98 | 62.31 | 130.40 |
| Gain in diabetes-free survival time (Years) | 0.11 | 0.06 | 0.11 |
| Intervention cost ($1000) | 126,929,900 | 31,358,600 | 41,007,400 |
| Aversion savings ($1000) | 78,026,160 | 47,145,420 | 79,031,520 |
| Total savings ($1000) | −48,903,740 | 15,786,820 | 38,024,120 |