Table 2.
Correlative comparisons between positive cellular expressions on neurons and glial cells for both antibodies used interleukin-6 (IL-6) and glial fibrillary acidic protein (GFAP) compared to the area of investigation, age, sex, post-mortem interval (PMI) and grading of GFAP staining intensity of the cases included.
| Group | Marker | Cell population | Localization | Age (in y) | Sex | PMI (in h) | Grading |
|---|---|---|---|---|---|---|---|
| Traumatic brain injury | IL-6 | Neuronal positive percentage | PCZ | 0.34 (*) | −0.13 | 0.00 | |
| CLC | 0.35 (*) | −0.06 | −0.04 | ||||
| HC | 0.27 | −0.03 | −0.22 | ||||
| CB | 0.07 | −0.01 | 0.06 | ||||
| Glial positive numbers | PCZ | 0.08 | 0.00 | −0.06 | |||
| CLC | 0.17 | −0.09 | −0.08 | ||||
| HC | 0.08 | −0.01 | 0.03 | ||||
| CB | 0.12 | −0.18 | 0.00 | ||||
| GFAP | Astrocytes positive numbers | PCZ | 0.03 | 0.01 | −0.13 | 0.38 (*) | |
| CLC | 0.28 | 0.01 | −0.02 | 0.35 (*) | |||
| HC | 0.07 | −0.14 | 0.22 | 0.45 (*) | |||
| CB | −0.12 | −0.02 | −0.01 | 0.45 (*) | |||
| Control | IL-6 | Neuronal positive percentage | PFC | −0.28 | 0.18 | 0.06 | |
| HC | −0.41 | 0.19 | 0.15 | ||||
| CB | −0.27 | 0.05 | −0.21 | ||||
| Glial positive numbers | PFC | −0.05 | −0.08 | 0.26 | |||
| HC | −0.10 | −0.41 | −0.03 | ||||
| CB | −0.26 | 0.18 | −0.15 | ||||
| GFAP | Astrocytes positive numbers | PFC | −0.02 | 0.59 (*) | 0.17 | 0.56 (*) | |
| HC | 0.26 | 0.51 | 0.32 | 0.61 (*) | |||
| CB | −0.19 | 0.64 (*) | 0.11 | 0.61 (*) |
PCZ, pericontusional zone; CLC, contralateral cortex; HC, hippocampus formation; CB, cerebellum; y, years; h, hours; *p < 0.05.