Table 3.

Modified Diagnostic criteria.

Diagnostic criteria
Proven IPA
Histopathologic, cytopathologic or direct microscopic examination of tissue invasion by septated, acutely branching filamentous fungi and/or by positive culture for Aspergillus in normally sterile specimen
Probable IPA
Host risk factor: Liver cirrhosis
AND
Clinical radiological features: abnormal radiological imaging compatible with lung infection
AND
Mycological evidence: direct test from BAL (cytology, direct microscopy or cultures) indicating the presence of Aspergillus spp. or galactomannan antigen detected in serum (ODI > 0, 5) or BAL (ODI > 1)
Possible IPA
Presence of a host factor and classical radiological features (dense, well-circumscribed lesion(s) with or without halo sign, air crescent sign and cavity), but absence of mycological criteria

Invasive pulmonary aspergillosis (IPA).