Structures of the BRCA1-A and BRISC-SHMT2α Complexes
(A) A cartoon representation of the BRCA1-A complex crystal structure.
(B) Schematic representation of the domain boundaries of BRCA1-A and BRISC-SHMT2α, showing parts present in the structure (domain cartoons and solid line), parts that are present in the construct but disordered in the structure (dashed line), and parts not present in the construct (grayed out domain cartoons and solid gray line).
(C) A cartoon representation of the BRISC-SHMT2α complex cryo-EM structure.