Figure 3. SRA1 down-regulated miR-9 in HPV-negative CSCC cells.

Linear regression revealed that miR-9 and SRA1 were inversely and significantly correlated in HPV-negative CSCC patients (A). Comparing with C and NC groups, expression levels of miR-9 and SRA1 were significantly up-regulated at 24 h after transfections (B). Moreover, SRA1 overexpression caused the down-regulated miR-9, while miR-9 overexpression failed to affect SRA1 expression (C) (*, P<0.05).