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. 2019 Jul 25;5(7):FSO407. doi: 10.2144/fsoa-2018-0124

Table 1. . Main antibacterial families (at least 5% of genera antibacterial except Fabaceae; see discussion), their known mechanisms of action, and active phytochemicals involved based on the references listed in Supplementary Table 1.

Family Known mechanism of action Primary active phytochemicals
Combretaceae Quorum sensing/biofilm inhibitor Flavonoids, e.g., catechin, naringenin; ellagic acid, ellagic acid derivatives, ellagitannins
Cupressaceae Quorum sensing/biofilm inhibitor Monoterpenes, e.g., limonene, α-pinene, δ-3-carene, α-terpinolene, camphor; sesquiterpenes, e.g., cedrol; polyphenols
Fabaceae Inhibits cell wall and/or membrane Phenolics, flavonoids
Lamiaceae Inhibits cell wall and/or membrane Terpenes/terpenoids, e.g., 1,8-cineole, pulegone, thymol, carvacrol, linalool, estragole, citral; carnosic acid; dihydroajugapitin; flavonoids, e.g., baicalin
Lauraceae Inhibits cell wall and/or membrane Aldehydes (e.g., cinnamaldehyde), aromatic alcohols (eugenol, benzyl alcohol); terpenoids (citral, citronellal, 1,8-cineole); endiandric acid and derivatives
Meliaceae Mechanism unknown Triterpenoid, e.g., limonoids
Myrtaceae Quorum sensing/biofilm inhibitor Monoterpenes, e.g., 1,8-cineole, α-pinene, α-terpineol; eugenol; flavonoids, e.g., quercetin
Zingiberaceae Inhibits cell wall and/or membrane Monoterpenes, e.g., 1,8-cineole, α-pinene, α-terpinene, β-pinene; flavonoids, e.g., isopanduratin A