Fig. 11. (a) Structure of the active site of myoglobin (PDB ID: 1YOI)135 showing relevant histidine residues and structure of Co-protoporphyrin IX (CoP, 1). (b) Cobalt catalysts (cobaloxime derivatives) inserted into a myoglobin matrix. (c) Scheme of the Ru–Fd–Co, 4 biohybrid, based on the structure of ferredoxin (PDB ID: ; 1A70) with a potential pathway for electron transfer from the PS to the catalyst. (d) Preparation of the artificial hydrogenase containing a {μ-(SCH2)2CHCOR}Fe2(CO)6 (7) moiety within a Q96C apo-nitrobindin (apoNB) (PDB ID for NB: ; 2A13).136.
