Fig. 7. The coordination sphere of the [NiFe] site in the D. fructosovorans hydrogenase (PDB: ; 1YRQ).101 Through site-directed mutagenesis, valine-74 has been shown to have a role in the gas accessibility to the active site, possibly through a gating action. Blue ribbon: large subunit; green ribbon: small subunit; heteroatom colour coding as in Fig. 1.
