Figure 2.

Amelioration of experimental aSAH by foramen magnum injection of DPSC-CM. Rat aSAH model was induced by the injection of fresh autologous blood into the cisterna magna. Induction of aSAH led to a diffuse vasoconstriction, predominantly in secondary and terminal cortical arterioles (middle). Administration of DPSC-CM via foramen magnum at the onset of aSAH induction effectively ameliorated the diffuse vasoconstriction (right). aSAH: aneurysmal subarachnoid hemorrhage. DPSC-CM: DPSC-derived conditioned media. “a”: artery. “v”: vein.