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. 2019 Jul 31;20(15):3747. doi: 10.3390/ijms20153747

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© 2019 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Improvement of neuro-cognitive impairments and motor dysfunctions in aSAH-injured rats by DPSC-CM. One week after the induction of aSAH, all experimental rats with indicated treatment were assigned for the Rotarod test (panel A). In aSAH-injured rats, induction of aSAH impaired the neurocognitive and motor functions, and treatment of DPSC-CM improved these impairments. Administration of IGF-1-neutralizing antibody moderately blunted the beneficial effect of DPSC-CM detected in the Rotarod test (panel B). * p < 0.05, ** p < 0.01, *** p < 0.001.