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. 2019 Jul 30;20(15):3727. doi: 10.3390/ijms20153727

Figure 4.

Figure 4

Effects of 100 nM ZM241285 (A2AR antagonist) on 100 nM CGS21680-evoked (A) and 20 μM CBZ-evoked (B) astroglial L-glutamate releases. Acute effects of A2AR antagonist (ZM: 100 nM) on 100 nM CGS21680-evoked L-glutamate release under the glutamate transporter functional (opened and gray) and blockade (green) are indicated in Figure 4A. Acute effects of A2AR antagonist on 20 μM CBZ-evoked L-glutamate release under the glutamate transporter functional (opened and gray) and blockade (green) are indicated in Figure 4B. Ordinates indicate mean levels of L-glutamate (μM) (N = 6). * p < 0.05 relative to control and # p < 0.05 relative to PDC by two-way ANOVA with Tukey’s post hoc test.