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. 2019 Jul 30;20(15):3727. doi: 10.3390/ijms20153727

Figure 6.

Figure 6

Interaction between chronic administration of cytokines and CBZ on basal, AdA-, and AMPA-evoked L-glutamate releases. Effects of chronic administration of IFNγ (100 IU/mL), TNFα (100 IU/mL), and CBZ (20 μM) on basal (opened) and 1 μM AdA-evoked (A, blue) L-glutamate release are indicated in Figure 6A. Effects of chronic administration of IFNγ (100 IU/mL), TNFα (100 IU/mL) with CBZ (20 μM) on basal (opened), and 100 μM AMPA-evoked (B, red) L-glutamate release are indicated in Figure 6B. Ordinates indicate mean levels of L-glutamate (μM) (N = 6). * p < 0.05 relative to non-CBZ and # p < 0.05 relative to control by two-way ANOVA with Tukey’s post hoc test.