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. 2019 Jul 25;20(15):3644. doi: 10.3390/ijms20153644
AFM atomic force microscope
AUC area under the indomethacin concentration-time curve
carbopol Carbopol® 934
COX cyclooxygenase
D diffusion constant within the skin
HPβCD 2-hydroxypropyl-β-cyclodextrin
IMC indomethacin
P-IMC gel transdermal formulations containing indomethacin solid microparticles
N-IMC gel transdermal formulations containing indomethacin solid nanoparticles
J c penetration rate
k a apparent absorption rate constant
k e elimination rate constant
K m skin/preparation partition coefficient
K p penetration coefficient through the skin
k r drug release rate constant
MC methylcellulose
P-IMC/MT gel transdermal formulations containing indomethacin solid microparticles and l-menthol
N-IMC/MT gel transdermal formulations containing indomethacin solid nanoparticles and l-menthol
NSAIDs non-steroidal anti-inflammatory drug
SC stratum corneum
SNPs solid nanoparticles
TDD transdermal drug delivery
t lag lag time
XRD powder X-ray diffraction