Figure 3.

Real-time measurement of change in interfacial potential at solution/dielectric interface of MCC-based ISFET sensor. Biotin-coated magnetic beads were utilized for the detection of streptavidin using the MCC-based ISFET sensor [(a) sample measurement], whereas an ISFET without magnetic beads was also prepared to estimate the effect of background noises such as the change in pH on the electrical signals of the MCC-based ISFET sensor [(b) control measurement]. The volume and concentration of the injected streptavidin solution were 20 μL and 180 μM, respectively.