Table 1.

Functional classification of 66 cancer-related proteins from Mel202-derived ectosomes. Proteins were selected with the use of the dbDEPC 3.0 database.

Cell Proliferation/Apoptosis	Cell Invasion and Metastasis	Cancer Cell Metabolism	Heat Shock Proteins and Chaperones	Drug Resistance	Others
Annexin A1 Annexin A2 Chloride intracellular channel protein 1 Heterogeneous nuclear ribonucleoprotein K Heterogeneous nuclear ribonucleoproteins C1/C2 Peptidyl-prolyl cis-trans isomerase A Peroxiredoxin-1 Peroxiredoxin-2 Peroxiredoxin-4 Peroxiredoxin-6 Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform Stress-induced-phosphoprotein 1 T-complex protein 1 subunit beta	14-3-3 protein zeta/delta Calreticulin Calumenin Cathepsin B Cathepsin D CD44 antigen Cell surface glycoprotein MUC18 Cofilin-1 Filamin-A Galectin-1 Galectin-3 Galectin-3-binding protein Histone H4 Integrin alpha-V Integrin beta-1 Keratin, type II cytoskeletal 5 Nucleoside diphosphate kinase A Phosphatidylethanolamine-binding protein 1 Profilin-1 Ras GTPase-activating protein-binding protein 1 Rho GDP-dissociation inhibitor 1 Serpin H1 Syntenin-1 Spectrin beta chain Superoxide dismutase [Cu-Zn] Vimentin WD repeat-containing protein 1	Apolipoprotein E Fatty acid synthase Fructose-bisphosphate aldolase A Glyceraldehyde-3-phosphate dehydrogenase Isocitrate dehydrogenase (NADP) cytoplasmic Lactoylglutathione lyase L-lactate dehydrogenase A chain Nicotinamide phosphoribosyltransferase Phosphoglycerate kinase 1 Pyruvate kinase isozymes M1/M2	60 kDa heat shock protein, mitochondrial precursor Alpha-crystallin B chain Endoplasmin Heat shock 70 kDa protein 1A/1B Heat shock 70 kDa protein 4 Heat shock protein beta-1 Heat shock protein HSP 90-beta	Glutathione S-transferase omega-1 Multidrug resistance-associated protein 1 Proliferating cell nuclear antigen	Elongation factor 1-beta Epoxide hydrolase 1 Glutathione S-transferase P Heterogeneous nuclear ribonucleoproteins A2/B1 Nucleophosmin Transforming growth factor-beta-induced protein ig-h3