Table 1.
Characteristics of formulations (mean ± SD, n = 3).
| Sample | Nanoemulsions | Nanocapsules | ||||||
|---|---|---|---|---|---|---|---|---|
| Size (nm) | PdI a | ζ (mV) b | Size (nm) | PdI a | ζ (mV) | Drug AE (%) c | ||
| Unloaded | 139.0 ± 3.8 | 0.170 ± 0.028 | −42.0 ± 4.5 | 131.7 ± 0.5 | 0.103 ± 0.004 | +46.0 ± 0.7 | - | |
| ECO 2 mM | 1312 ± 131 | 0.763 ± 0.06 | +1.48 ± 1.6 | 127.1 ± 1.5 | 0.107 ± 0.017 | +33.0 ± 1.0 | 87.2 ± 6.1 | |
| TIO 5 mM | 2215 ± 1348 | 0.9 ± 0.173 | −5.19 ± 1.3 | 146.8 ± 0.8 | 0.079 ± 0.019 | +24.7 ± 1.1 | 99.0 ± 0.8 | |
a Polydispersity Index. b Zeta potential. c Drug Association Efficiency (%) = [(Conc. drugtotal − Conc. drugunloaded) / (Conc. drugtotal)] × 100.