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Helical wheel analyses of some of the most prominent representatives of apo-AI mimetic peptides. The peptides belong to class A amphipathic helices [55]. The hydrophobic and hydrophilic residues are grouped on opposing faces with the negatively charged residues being aligned preferentially on the polar phase, while the aromatic residues are rather located on the non-polar face being involved in lipid binding [67]. The helical wheel is obtained with the program HeliQuest [68].
