Table 1.
→Epidermis →Dermis |
Cytokine/Chemokine | Receptor | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
ET-1 | SCF | GROa | HGF | bFGF | KGF | IL-1a | TNFa | EDNBR | c-KIT | KGFR | |
UVB melanosis | ↑ | ↑ | → | → | ↑ | ↑ | ↑ | → | ↑ | → | ↑ |
Solar Lentigo | ↑ | ↑ | → | ? | → | ↑ | ↓ | ↑ | ↑ | ↗ | ↑ |
Seborrehoic Keratosis | ↑ | ⇡ | ? | ? | ? | ? | ↓ | ↑ | ? | ? | ? |
Dermato-fibroma |
→
→ |
↑
→ |
→
→ |
↑
→ |
→
→ |
? | ? | ? | ? | ↑ | ? |
Café-au-lait
macules |
→
→ |
↑ | ? | ↑ | → | ? | ? | ? | ? | ? | ? |
Riehl’s Melanosis | ? | ? | ↑ | ? | ? | ? | ↑ | ? | ? | ? | ? |
Vitiligo Vulgaris | ↑ | ↑ | ? | → | → | ? | ? | ? | → | ↓ | ? |